Glycolaldehyde dehydrogenase

Yoshiki (29) has studied the biosynthetic pathways of vitamin Bg, including the discovery of the precursor glycolaldehyde, glycolaldehyde dehydrogenase, and isolation of microorganisms deficient in regulation mechanism of Bg biosynthesis. 

Scheme 1.—The Reactions Involved in the Enzymic Determination of (a) Glycerol, (b) Erythritol, (c) Glycolaldehyde, and (d) and (e) Formic Acid. [Abbreviations ATP, adenosine 5 -triphosphate ADP, adenosine S -pyrophosphate NAD and NADH, the oxidized and reduced forms of nicotinamide adenine dinucleotide PEP, enolpyruvate phosphate Pi, inorganic orthophosphate GK, glycerol kinase GDH, u-glycerophosphate dehydrogenase EK, erythritol kinase PK, pyruvate kinase YAD, yeast alcohol dehydrogenase FS, formyltetrahydrofolate synthetase FD, formate dehydrogenase and NR, nitrate reductase.]...

A more complex example, triosephosphate dehydrogenase, is strongly inhibited by a tetrose bisphosphate that contaminates preparations of glycolaldehyde phosphate, of which it is a condensation product. The... 

Glycolaldehyde has been isolated as a product of pentose cleavage by Acetobacter ocetigenumA Dehydrogenases for this diose have been described in liveri and yeast, the latter enzyme being TPN-specific. It should be noted that glycolaldehyde and acetic acid are at the same overall oxidation level. 

---