Glycol-cleavage oxidation polysaccharides

Floor, M., Glycol-Cleavage Oxidation of Polysaccharides and Model Compounds Calcium Complexation of Dicarboxy Glucans, Ph.D. thesis, Delft University of Technology, Delft, The Netherlands, 1989. 

Historically, developments in chromatography led to a marked growth in research on polysaccharides and carbohydrate-containing biopolymers, which commonly entailed glycol-cleavage oxidation. With time, NMR spectroscopy and mass spectroscopy have acquired complementary roles of ever-increasing importance in studies on molecular structure. 

Aside from its role in the structure determination of polysaccharides, glycol-cleavage oxidation is applied widely in studies on various carbohydrate-containing macromolecules of biological interest. In most of the following examples the oxidation is used to alter sugar residues selectively, either to focus attention on the biochemical nature of the carbohydrate part, the protein, or some other constituent. 

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