Glycerin tributyrate

Enzymes are active in organic solvents at low water contents. Porcine pancreatic lipase in glycerin tributyrate (tributyrin) shows, for 0.015% water in the tributyrin—pentanol reaction mixture, a rate of transesterification comparable to the value in aqueous solution (Klibanov, 1986 Zaks and Klibanov, 1984). The water content of the protein in the above reaction mixture was 0.01—0.03 h. This is below the level expected for the onset of enzyme activity in protein—water powders. Nonaqueous solvents can produce change in the substrate specificity of an enzyme (Zaks and Klibanov, 1986 Zaks and Klibanov, 1988a) and possibly can lock the enzyme into a more active conformation (Russell and Klibanov, 1988). The dependence of the catalytic activity on added water has been measured for several enzymes in several solvents (Zaks and Klibanov, 1988b). 

Synonyms Glycerin tributyrate Glycerol tributanoate Tributanoin Source Chrastil, J. J. Phys. Chem. (1982), 86(15), 3016-3021. 

Synonyms Glycerin tributyrate Glycerol tributanoate Tributanoin Source Hammam, H. J. Supercrit. Fluids (1992), 5(2), 101-106. 

BUTYRIC. YCID TRIESTER with GLYCERIN BLTTYR-YL TRIGLYCERIDE FEMANo. 2223 GLYCEROL TRIBUTYRATE KODAFLEX TRIBUTYROIN... 

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