Glyceraldehyde 2- deoxy-2-fluoro

The cycloaddition of the 2,4-dialkoxy-l,l-difluoro-bata-l,3-diene 11 to benzyloxyacetaldehyde has afforded the unsaturated pyranoside 12 from which die racemic 2,4-dideoxy-4,4-difluotopyranosides 13 were obtained. The synthesis of 2-deoxy-2,2-difluoro-D-ribono-l,4-lactDne has been achieved by application of the Refomiatsl reaction of an ethyl difluoroacetate derivative with 2,3-0-cyclohexylidene-D-glyceraldehyde. A study of the formation of 6-deoxy-6-fluoTohexonolactones from 5,6-anhydro-hexonolactones and of 2-deoxy-2-fluoropentone-l,4-l tones from 2,3-anhydro-pentono-l,4-lactones has been reported, and the synthesis of some 3-amino-2,3-dideoxy-2-fluoro-D-xylose derivatives has been reported. ... 

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