Glutathione disulfide anion radical

Ramakrishna Rao, D. N., Fischer, V., Mason, R. R Glutathione and ascorbate reduction of the acetaminophen radical formed by peroxidase. Detection of the glutathione disulfide radical anion and the ascorbyl radical. J. Biol. Chem. 1990, 265, 844—847. 

The reduction potentials of thiyl radicals and disulfide aniones in Table 7 are of interest because of the importance of sulfhydryls in biological systems and the involvement of glutathione (GSH) as a cellular protective agent [72]. Of primary... 

Thiyi radicals and disulfide radical anions exhibit reasonably characteristic optical absorptions for detection by spectroscopic methods. Practically all aliphatic thiyi radicals display an absorption band in the UV with around 330 nm with extinction coefficients typically less than 500 M cm". Exceptions with respect to the extinction coefficients (e) appear to be the thiyi radicals derived from penicillamine and glutathione, PenS and GS, which for some as yet unidentified reason have higher values of ca. 1200 and 800 M" cm", respectively [34],... 

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