Glutaraldehyde, Schiff base condensation

Fig. 19. Schiff base condensation of glutaraldehyde with enzyme amino...

Condensation reactions of aniline and of other bases with aromatic aldehydes to give Schiff s bases are accelerated by ultraviolet light in buffered media. For example, o-phenylenediamine reacts with formic acid to yield benzimidazole and acetylacetone reacts with guanidine to form 2-amino-4,6-dimethylpyrimidine.162 Similarly, lobelanine is formed by the photocondensation of glutaraldehyde, benzoylacetic acid, and methylamine hydrochloride.163... 

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