Glucopyranosyl fluorides 3 anomer

The lower reactivity of a-D-glucopyranosyl fluoride permits its etherification with triphenylmethyl chloride in pyridine without formation of the quaternary compound the product is 6-0-trityl-a-D-glucopyranosyl fluoride. A similar process, leading, however, to the jS-D anomer, can be carried out if a sterically hindered base, 2,6-dimethylpyridine, is used instead of the pyridine. ... 

Treatment of the acylated glycosyl halide (bromide or chloride) of the opposite anomeric configuration with silver fluoride in acetonitrile was the method initially developed40 for the synthesis of the less stable anomers, as exemplified by the synthesis of peracylated /S-D-glucopyranosyl fluoride40 from the corresponding a-bromide. It has... 

---