Gingerol homologs

Figure 8. Tracings of TLC separations of the homologs of gingerol and shogaol. Conditions of separation for Spots 1 and 2 according to (40) 3 and 4 according to (42) 5, 6, ana 7 according to (43). Spots 2, 4, and 6 sprayed with phenol reagent 7 sprayed with 2,4 DNPH reagent spots 1, 3, and 5 cochromatographed spots,...

Main components 1.5-3% essential oil, 5-8% sharp tasting resin with the homologous gingerols, as well as shogaols, zingerone and others, starch, sugar, fat and organic acids. 

The (S)-(+)-gingerols, 4-hydroxy-3-methoxy-(5S-hydroxy-3-oxoalkyl)benzenes, comprise a group of homologous C10, C12 and C14 compounds. The last (Fig (3)-8), has been synthesised from 4-hydroxy-3-methoxycinamic acid [245]. 

Apart from the hydroxy pentadecyl compounds reported in the orsellinic series (ref. 14), the long chain compounds constituting the gingerols, for example, 4-hydroxy-3-methoxy-(5 -hydroxy-3 -oxoalkyl)ben2enes have attracted synthetic interest. Thus three members of the (+)-(S)-gingerol series, the C q side chain compound, designated (+)(S)[6], and the homologous C 2 14 compounds have been... 

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