Giese method alkenes

Curran2 has reviewed recent applications of the tin hydride method for initiation of radical chain reactions in organic synthesis (191 references). The review covers intermolecular additions of radicals to alkenes (Giese reaction) as well as intramolecular radical cyclizations, including use of vinyl radical cyclization. 

A concise collection of some modem methods of radical formation via rupture of C-E, C-G and C-A bonds, as well as from alkenes and cyclopropanes, by metals, organometallic hydrides, and photochemical and electrochemical means, are given in the last Chapter of Giese s book [28]. For some examples of radical generation and reactions leading to cyclic and polycyclic compounds see next Chapter (Heading 6.1.3). 

Metal-metal bond photolysis has found practical synthetic use in C-C bond-forming reactions. The metal-trapping reaction (Equation (10)) is used to generate an organic radical, which subsequently reacts with an alkene to form saturated and/or unsaturated products (Scheme 2). Giese has extensively developed this reaction for synthetic purposes, and reports that Cp2Fe2(GO)4 and Mn2(CO)io are both practical M-M bond precursors in these reactions. The method is also valuable for carrying out intramolecular cyclization reactions (Equation (12)). 

---