Giant-cell glioblastoma

FIGURE 20.30 This giant cell glioblastoma has a relatively abrupt margin with brown NF-positive cerebral white matter. However, near the appropriately NF-negative vessel and large abnormal mitotic spindle, the tumor infiltrates between brown long axons. 

Martinez-Diaz H, Kleinschmidt-DeMasters BK, Powell SZ, et al. Giant cell glioblastoma and pleomorphic xanthoastrocytoma show different immunohistochemical profiles for neuronal antigens and p53 but share reactivity for class III beta-tubulin. Arch Pathol Lab Med. 2003 127 1187-1191. 

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