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General Survey of Substituents on Carbon

Nitration of 1-phenylindazole (176) in 86% nitric acid gives l-phenyl-4-nitroindazole (177) when [Pg.46]

2-phenylindazole (178) is nitrated in the cold, two mononitro compounds (m.p. 170°C and 184°C) were isolated but not identified 93.AHC(58)215 . Preparation of 2-p-nitrophenylindazole (m.p. 224-226 °C) can be achieved by reaction of indazole withp-fluoronitrobenzene in PTC conditions without solvent 93SC1947 , thus the unknown mononitro derivatives of 2-phenylindazole are probably nitrated on the indazole ring. [Pg.46]

If the reactions of the same substituents on heteroaromatic azoles and on benzene rings are compared, the differences in the reactivities are a measure of the heteroatoms influence. Such influence by the mesomeric effect is smaller when the substituent is (3 to a heteroatom than when it is a or y. The influence by the inductive effect is largest when the substituent is a to a heteroatom. [Pg.433]


General Survey of Substituents on Carbon Nucleophilic Displacement Electrophilic Attack Metal-Catalyzed Substitution... [Pg.915]


See other pages where General Survey of Substituents on Carbon is mentioned: [Pg.40]    [Pg.81]    [Pg.167]    [Pg.257]    [Pg.487]    [Pg.497]    [Pg.307]    [Pg.321]    [Pg.925]    [Pg.433]    [Pg.679]    [Pg.704]    [Pg.235]    [Pg.273]    [Pg.463]    [Pg.478]    [Pg.475]    [Pg.555]    [Pg.40]    [Pg.81]    [Pg.167]    [Pg.257]    [Pg.40]    [Pg.81]    [Pg.167]    [Pg.257]    [Pg.46]    [Pg.235]    [Pg.273]    [Pg.463]    [Pg.478]   


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Carbon generality

General survey

Substituent survey

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