General Procedures of Aza MBH Reactions Involving Aliphatic Imines

General Procedures of Aza-MBH Reactions Involving Aliphatic Imines pi] 

To a solution of corresponding imine freshly prepared (1.0 equiv) in dried dichlor omethane at 0 °C, catalyst (13c) (0.1 equiv), (3 naphthol (0.1 equiv), and P naphthyl acrylate (2.0 equiv) were added. The reaction mixture was stirred under argon atmosphere at 0 °C for the required time indicated in the tables. The reaction was stopped by passing the mixture through a short pad of silica gel using ethyle acetate for the elution. Solvents were removed in vacuo and the residue was purified by flash chromatography on silica gel (eluent n Hept/EtOAc = 90/10) to afford the corre spending pure product. 

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