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General partial-synthesis functions

Ethyl 2-amino-l,4,5,6-tetrahydropyridine-3-carboxylate (13) is obtained under mild conditions by mutual treatment of 3-carbethoxy-2-piperidinone (12) with triethyloxonium tetrafluoroborate and then ammonia.13 The synthesis of /J-enamino esters such as 2-amino-l-aryl-3-carbethoxypyrrolin-4-one (15) possessing a carbonyl function in the partially saturated ring is accomplished by cyclization of ethyl y-chloro-oc-cyano-acetoacetate (14) with arylamines.14 As H-NMR spectra show, 15 exists predominantly in the / -dicarbonylenamine form (Scheme 5). Furthermore, furanones of the general... [Pg.303]


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Functional general

Functional synthesis

Functionalized synthesis

Functions synthesis

General functions

Partial function

Partial synthesis

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