Gaussian globule

Equations (2.2.12)-(2.2.14) define the so-called random Gaussian globule resulting from coil collapse in words, all the long-range mean-square distances with Ic > J are equal, whereas those between relatively close atoms... 

It is necessary to consider different regimes dependent on the dimensions of polymer chains. A long chain collapses into a globule consisting of close-packed blobs of size The blobs are either Gaussian or swollen depending on the second virial coefficient value. In a 0 solvent, the chain radius in the collapsed state is given by ... 

Each cell of your body contains about ten centimeters to one meter of DNA, and this DNA must fit into a micron-sized cell nucleus. The DNA is far too big to fit into the cell not only as a straight stick, but even as a Gaussian coil (we mentioned this already in Chapter 5). Therefore, DNA in the cell must be somehow condensed and, from a polymer physics point of view, it must be in the state of globule, albeit quite pecuhar one (see also Section 9.13 about the concept of globule in this case). 

Unlikely the previous calculations of AF of the coil-globule transition, where the Gaussian distribution of segments in a macrornolecule was assumed (eg. see Equation 2), Bir-shtein and Pryainitsyn (1987) have applied Fixman s (1962) distribution function valid for the range R Rs... 

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