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Gastric emptying-slowing agents

Because the antimuscarinic drugs slow gastric emptying, they may increase symptoms in patients with gastric ulcer. Nonselective antimuscarinic agents should never be used to treat acid-peptic disease (see Chapter 62). [Pg.164]

The antiemetic properties of metoclopramide appear to be a result of its antagonism of central and peripheral dopamine receptors. Dopamine produces nausea and vomiting by stimulation of the medullary chemoreceptor trigger zone (CTZ), and metoclopramide blocks stimulation of the CTZ by agents like levodopa or apomorphine that are known to increase dopamine levels or to possess dopaminelike effects. Metoclopramide also inhibits the central and peripheral effects of apomorphine and abolishes the slowing of gastric emptying caused by apomorphine. [Pg.437]

See other pages where Gastric emptying-slowing agents is mentioned: [Pg.91]    [Pg.96]    [Pg.96]    [Pg.97]    [Pg.91]    [Pg.96]    [Pg.96]    [Pg.97]    [Pg.225]    [Pg.507]    [Pg.673]    [Pg.315]    [Pg.464]    [Pg.401]    [Pg.275]    [Pg.276]    [Pg.947]    [Pg.660]    [Pg.1017]    [Pg.153]    [Pg.61]    [Pg.964]    [Pg.260]    [Pg.531]    [Pg.50]    [Pg.237]   
See also in sourсe #XX -- [ Pg.91 , Pg.96 ]



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