Gallocatechin 3-gallate flavan

Gallocatechin 3-gallate (flavan-3-ol) Davidsonia pruriens (Davidsoniaceae), Hamamelis virginiana (Hamamelidaceae), Camellia sinensis (Theaceae) Proteasome CHY-like activity (187 nM) [100]... 

Figure 1.6 Computer-generated stereochemical projections for flavan-3-ol diastereoisomers. EGCG, epi-gallocatechin gallate GCG, gallocatechin gallate. Three dimensional structures computed by Professor David Lewis, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.

Grape peel and seeds are especially rich in the flavan-3-ols, catechin, epicatechin, gallocatechin, epigallocatechin, epicatechin gallate and catechin gallate (Fig. 3). The content in the peel varies greatly (10-520 mg/kg), since it depends on the cultivar and seasonal and environmental factors [16]. In addition, the occurrence of the flavanonols astilbin (dihydroquercetin 3-rhamnoside) and engeletin (dihydrokaempferol 3-rhamnoside) has been described. 

Flavan-3-ols (+)-Catechin (-)-Epicatechin (-)-Epicatechin 3-gal late (-)-Epigallocatechin-3- gallate (-F)-Gallocatechin (-)-Epigallocatechin Procyanidins Prodelphinidins Apples, apricots, grapes, peaches, nectarines, raspberries, cherries, blackberries, blueberries, cranberries, pears, plums, and raisins [14]... 

Flavanols (Flavan-3-ols), found in the seed and skin, are the most abundant class of flavonoids in grapes. These are often specifically called the flavan-3-ols to identify the location of the hydroxy group on the C ring. The five common flavan-3-ol monomers found in grape skins are (+)-catechin (C), (-)-gallocatechin (GC), (-)-epicatechin (EC), (-)-epigallocatechin (EGC), and (-)-epicatechin 3-gallate (ECG). 

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