Fundamentals of Chromatography

The various theoretical and practical aspects of the use of HPLC methods have been recently discussed in exquisite books, such as the application of HPLC-MS in drug analysis [59], the theory of chromatography [60], the fundamentals of chromatography [61, 62], the practice and theory of ion-chromatography [63], problem solving in HPLC [64], the... 

The fundamentals of chromatography are not covered in detail the reader is referred to one of the introductory textbooks or courses on the subject. 

H. G. CASSIDY Fundamentals of Chromatography, chap. 10, Interscience, New York, 1957. 

During the development of modern liquid chromatography, advances have been driven by both instrumentation and chemistry. The technique as now practiced produces elegant separations that have been developed through chemical manipulation of the stationary and mobile phases, which are then effected and detected by modern instrumentation. This chapter is therefore divided into three broad sections the first, on the fundamentals of chromatography, provides the necessary foundation for the second, on instrumentation, and the third, on separation modes. 

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