Fujita advantages

Although Meyer and Overton used olive oil for their measurements of hydrophobicity, Hansch and Fujita rejected it because the composition varies from lot to lot. Instead they chose to do the measurements in 1-octanol, which is available commercially in pure form. Octanol has the advantage over pure... 

In comparison with the classical version of the Free Wilson analysis, the Fujita Ban variant offers a number of important advantages ... 

The newly-developed dichotomy has advantages over the conventional dichotomy between enantiomers and diastereomers (the broken-Uned boxes in Fig. 10.11), because the latter causes the confusion due to the entangled criteria shown in Table 10.3. This means that a paradigm shift from the conventional terminology to the present terminology for stereoisomerism turns out to be inevitable (Fig. 10.11) (Fujita 2009e), where correspondence between terms for relationships and those for attributes are defined as follow enantiomeric — chiral f S -diastereomeric — f S -stereogenic and l 5-stereoisomeric — f 5-stereoisomerism. 

In this section, the URP (updated reference-point) method proposed originally for stochastic input is explained (Fujita and Takewaki 2011a). This method can be used as an efficient uncertainty analysis to obtain the robustness function a explained in the previous section. Since the URP method takes full advantage of an approximation of first- and second-order Taylor series expansion in the interval analysis, the formulation of Taylor series expansion in the interval analysis and the achievement of second-order Taylor series expansion proposed by Chen et al. (2009) are explained briefly. 

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