Fructose 1,6-bisphosphate Frul

FIGURE 1.2 (continued from page 10) PDH complex activity, leading to the production of more acetyl-CoA, resulting in enhanced accumulation of seed oil (Zou et al. 1999, Marillia et al. 2003). The precise mechanism by which mitochondrial acetyl-CoA promotes enhanced seed oil accumulation remains to be elucidated. Additional metabolites Fru 1,6BP, fructose-1, 6-bisphosphate (Frul,6BP) OAA, oxaloacetate PEP, phosphoenolpyruvate. Additional information for the depicted scheme is available in the work of Ruuska et al. (2004). 

Glucose (Glc) is taken up and phosphorylated into glucose-6-phosphate (Glc6P), with consumption of ATP. Isomerization and phosphorylation afford fructose-l,6-bisphosphate (Frul,6P2), which is cleaved into two triose molecules D-glyceraldehyde-3-phosphate (GA3P) and dihydroxyacetone monophosphate (DHAP). These are equilibrated by triose phosphate isomerase as only GA3P is metabolized further, except approximately 5 mol% of DHAP that leaks out of the pathway via reduction to glycerol, which is excreted as a side-product. 

Fig. 8.4 The glycolysis pathway in Saccharo-myces and the biosynthesis of ethanol and glycerol. Compounds DHAP, dihydroxyl-acetone monophosphate Fru6P, D-fructose-6-phosphate Frul,6P2, D-fructose-1,6-bisphosphate GA3P, D-glyceraldehyde-3-phosphate GL3P, sn-glycerol-3-phosphate GLAP2, phosphoglycerate-3-phosphate ...

---

See also in sourсe #XX -- [ , , , , ]

---