From Glucose to UDP-N-Acetylhexosamine

Enzyme EC number Substrates Effectors Regulatory enzyujg Location References 

1 glucosamine-6-phosphate synthase 5.3.1.19 Fru-6-P, glutamine Glc-6-P, AMP, UTP UDP-GlcNAc + cytosol WiNTERBURN and Phelps 1971 a 

2 glucosamine-6-phosphate deaminase 5.3.1.10 GlcN-6-P GlcNAc-6-P 7 cytosol, membranes Comb and Roseman 1958 b 

3 glucosamine-6-phosphate N-acetyltransferase 2.3.1.4 GlcN-6-P, AcCoA — ( + ) cytosol CoRFIELD 1973 

4 N-acetylglucosamine-6-phosphate mutase 2.7.5.2 GlcNAc-6-P — — cytosol Reissig and Leloir 1966 

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