Forster reaction synthesis from oximes

This reaction was initially reported by Forster in 1915. It is the synthesis of diazoketones, especially for the cyclic diazoketones from a-keto oximes by the reaction with chloramines. Therefore, it is known as the Forster reaction. Although two mechanisms have been proposed for this reaction,experimental evidence favors the one involving the attack of NH2CI by the lone-pair electrons of the oxime nitrogen. " This reaction has been modified via the generation of chloramine in situ, which is used in the preparation of 2-diazo-1 -indanones. ... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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