Formic-pivalic anhydride

Rosenau, T., Potthast, A., Ebner, G., Kosma, P. Deoxygenation of amine oxides by in-situ-generated formic pivalic anhydride. Syn/eff 1999, 623-625. 

The synthesis of michellamine A (6) from korupensamine A (198) commenced with the N-formylation of 198 with pivalic formic anhydride (Scheme 27). Subsequent treatment with acetyl chloride provided diacetate 210 where the chelated C-5 hydroxy group was not protected. Dimerization was then achieved under conditions described by Laatsch for simple naphthol dimerisation (ref. 88) which involved treatment of with Ag20 in chloroform in the presence of... 

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