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Fluoropyridines nucleophilic displacements

Functionalization at N-1 by Use of Electrophiles. The nucleophilic displacement of activated arenes and electrophiles affords convenient access to functionalized benzopyrazoles. The reaction of benzop3Tazole with 3-fluoropyridine using sodium hydride affords the V-arylatedproducts with the majorproduct being theV-l arylated regioisomer. Similar reactivity is displayed in the reaction of benzopyrazole with 4-fluoronitrobenzene and pentaflu-orobenzene (eqs 10-12). ... [Pg.36]


See other pages where Fluoropyridines nucleophilic displacements is mentioned: [Pg.207]    [Pg.151]    [Pg.207]    [Pg.207]    [Pg.170]    [Pg.24]    [Pg.456]    [Pg.450]    [Pg.350]    [Pg.136]    [Pg.152]    [Pg.152]    [Pg.153]    [Pg.349]    [Pg.363]    [Pg.423]   
See also in sourсe #XX -- [ Pg.133 ]




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2- fluoropyridine

Nucleophilic displacement

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