Fluorescent silica nanopartides

Various types of fluorescent silica nanopartide have been developed some details are summarized in Table 4.7. Fluorescent dyes are attached to silica nanopartides by several means, as indicated in the table. For example, they can be incorporated... 

Ow, H., Larson, D.R., Srivastava, M., Baird, B.A., Webb, W.W. and Wiesner, U. (2005) Bright and stable core-shell fluorescent silica nanopartides. Nano Letters, 5,113-17. 

Santra, S., liesenfeld, B., Dutta, D., Chatel, D., Batich, C.D., Tan, W., Moudgil, B.M. and Meride, R.A. (2005) Folate conjugated fluorescent silica nanopartides for labeling neoplastic cells. Journal of Nanoscience and Nanotechnology, 5, 899-904. 

Tleugabulova, D., Zhang, Z., Chen, Y., Brook, M.A. and Brennan, J.D. (2004) Fluorescence anisotropy in studies of solute interactions with covalently modified colloidal silica nanopartides. Langmuir, 20, 848—854. 

Stanley, J.T., Walters, G.A., Tan, W.H., Moudgil, B.J. and Meride, R.A. (2005) Synthesis and characterization of fluorescent, radio-opaque, and paramagnetic silica nanopartides for multimodal bioimaging applications. Advanced Materials, 17, 2165-9. 

Figure 7.4 Penetration of different-sized silica nanopartides (NP) through the membranes of A549 cells. Large-NP 85 nm small-NP 23 nm. Both NPs are fluorescent and monitored by their fluorescent color (yellow) under the confocal fluorescence microscope. Reprinted with permission from Ref [82] 2007, American Chemical Society.

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