Flexible redox polymers, electrical wiring

Figure 13. A redox enzyme electrically wired to an electrode surface by flexible polymer chains functionalized with redox-mediator groups and surrounding the enzyme at the electrode surface.

Relevant issues still to be addressed in constructing amperometric enzyme sensors either using the electrical wiring of enzymes with redox polymers or with flexible polymeric electron mediators are sensor efficiency, accuracy, reproducibility, selectivity, insensitivity to partial pressure of oxygen, detectivity (signal-to-noise ratio) as well as sensor hfetime and biocompatibility [47]. Then we can address manufacturability and the cost of use of either in vitro or in vivo sensors. 

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