Fletcher-Campbell

Fletcher-Campbell, F. (1994) Still Joining Forces A Follow-up Study of Links between Ordinary and Special Schools, Slough NFER. 

We have reviewed this class of retro- and retro-inverso-peptide analogues previously.1[2 3 72] Since then, Fletcher and Campbell 73 have published a comprehensive review on PMRI-peptides. It also covers a wide range of synthetic methodologies related to the synthesis of substituted malonates and gem-diaminoalkyl residues. 

Interestingly, a host of methods for the preparation of orthogonally protected a-aminogly-cine191-931 and a-aminoalanine 94 95 have been reported. However, their applicability to the synthesis of PMRI-peptides is limited. Additional, less general methods have been extensively reviewed by Fletcher and Campbell. 73 ... 

Fletcher, M. D., Campbell, M. M. Partially Modified Retro-Inverso Peptides Development, Synthesis, and Conformational Behavior. Chem. Rev. 1998, 98, 763-796. 

The author would like to thank Al Campbell, Dave Lidzey, Rob Fletcher, Colin Dooling, Pierre Oliviere and O. Worsfold for helpful discussions during the preparation of this chapter. 

---