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Quinine Flecainide

FLECAINIDE QUININE Quinine may T flecainide levels Quinine inhibits CYP2D6-mediated metabolism of flecainide The effect seems to be slight, but watch for flecainide toxicity monitor PR and BP closely... [Pg.20]

Flecainide is metabolized by CYP2D6, and is subject to poljmorphic metabohsm. In extensive metabolizers its clearance is reduced by quinine (74). Quinidine reduces the clearance of R-flecainide but not that of 5-flecainide (75). [Pg.1374]

Munafo A, Reymond-Michel G, Biollaz J. Altered flecainide disposition in healthy volunteers taking quinine. Eur J Clin Pharmacol 1990 38(3) 269-73. [Pg.1375]

Simultaneous N-acetylprocainamide, ajmaline, chlorpromeizine, desipramine, dipyridamole, doxazosin, flecainide, durazepam, gallopamil, imipramine, keteuiserin, metoprolol, mexiletine, mianserin, nadolol, nitrazepam, orphenadrine, oxprenolol, penbutolol, pindolol, prqjmalium, procainamide, propranolol, protriptyline, p3Timethamine, quinidine, quinine, triamterene, trimipramine, verapamil... [Pg.1303]

Quinidine and quinine cause a modest reduction in the clearance of flecainide. [Pg.259]

See other pages where Quinine Flecainide is mentioned: [Pg.408]    [Pg.60]    [Pg.124]    [Pg.142]    [Pg.228]    [Pg.384]    [Pg.403]    [Pg.489]    [Pg.519]    [Pg.622]    [Pg.745]    [Pg.801]    [Pg.1002]    [Pg.1047]    [Pg.1210]    [Pg.259]    [Pg.60]    [Pg.124]    [Pg.142]    [Pg.228]    [Pg.384]    [Pg.489]    [Pg.519]    [Pg.622]    [Pg.745]    [Pg.801]    [Pg.1002]    [Pg.1047]    [Pg.1210]    [Pg.36]   
See also in sourсe #XX -- [ Pg.259 ]



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Flecainide

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