Flavors dihydrofurans

For synthetic purposes the prime oxidation is that leading to 2,5-dihydroxy-dihydrofuran derivatives as in Schemes 55 and 56. Thus 5-methylfurfuryl alcohol 115 can be transformed in stages outlined in Scheme 58a to the cyclopentenone 116 which is an important substance affecting the flavor of... 

Oxidation. As one step in the synthesis of furaneol (3, a flavor principle of pineapples and strawberries), Buchi et a . wished to effect hydroxylation of 2,5-dimethyl-2,5-dimethoxy-2,5-dihydrofurane (1). They tried oxidation of(1 15.8 mmole) with potassium chlorate (22.8 mmole) and osmium tetroxide (0.3 mmole) in aqueous letrahydro-furane containing sodium bicarbonate at 30° for 63 hr. however, the expected diol... 

Biichi G. Demole E. and A.F. Thomas A.F. (1973) Synthesis of 2,5-dimethyl-4-hydroxy-2,3-dihydrofuran-3-one (furaneol), a flavor principle of pineapple and strawberry. J. Org. Chem. 38, 123. 

Uses Fragrance in cosmetics, perfumes flavoring agent in foods Manuf./Distrib. Aldrich http //www.sigma-aldrich.com, ICN Biomed. Research Prods. http //www.icnbiomed.com, Lancaster Synthesis Penta Mfg. http //www.pentamfg. com 2,3-Dihydrofuran... 

Electrooxidation of hetero-aromatic com-potmds furnishes an efficient access to useful chemicals for instance, electrolysis of 2-(l-hydroxyethyl)furan in methanol affords the corresponding 2,5-dimethoxy-2,5-dihydrofuran, and subsequent few steps of the reactions lead to maltol, an important flavor [16]. 

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