Fibrous hamartoma

Fig. 20.4. Fibrous hamartoma of the corpora cavernosa. Coronal T2-weighted image showing relatively low signal intensity tissue ( ) replacing wide portions of the normal hyperintense cavernosal tissue...

Bertaccini A, Marchiori D, Giovannini C et al (2004) Fibrous hamartoma of corpus cavernosum a rare cause of congenital penile curvature associated with erectile dysfunction. J Urol 172 642-643... 

Bile-duct adenomas are rare. Usually, they are solitary and < 2 cm in size. This type of adenoma is more often detected in men than in women (3 1) and it occurs in patients mainly over the age of 50. It is nearly always localized beneath the liver capsule. This adenoma has the form of a firm, whitish node and consists of bile-duct proliferations. It contains biliary acini and tubules which are lined with a layer of cuboid epithelium within loose fibrous, partially hyaline stroma. There is evidence of mononuclear inflammatory cells and, occasionally, lymph follicles. It is discussed that such biliary adenomas are peribiliary gland hamartomas. (162) There are no clinical or biochemical abnormalities, nor is there any tendency towards malignant degeneration. (161,163)... 

Benign biliary microhamartomas (= Meyenburg s complex) were described by H. von Meyenburg in 1918. They consist of small cysts developing from dilatations of the small (interlobular) bile ducts and are surrounded by fibrous stroma. The cysts are remnants of ductal plate malformations. Occasionally, typical ductal plates can also be detected. The hamartomas can reach a diameter of up to 0.5 (-1.0) cm. (s. fig. 32.18) Macroscopically,... 

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