Fibrinogen sprayed onto surfaces

Figure 3. Fibrinogen sprayed onto surfaces of polystyrene (Panels A,B,C,and E), and carbon (Panel D). In panel E the alpha chain extension has been enzymatically removed. The scale bar represents 50nm.

Figure 2. Panel A is purified human fibrinogen sprayed onto the surface of thin carbon films. Panels B-F are of purified human fibrinogen reacted with fabs specific to a portion of the alpha chain extension (B), the D-domain (terminal nodule) of fibrinogen (C and D), and the E-domain (central nodule)of fibrinogep (E and F). The scale bar represents 50 nm.

Figure 1. Carbon films are exposed to static, citrated whole blood. Panel A is the control surface with no exposure to blood, Panel B is a 5 sec. exposure, and panel D is a 60 sec. exposure. Panel C is plasma diluted 1 1000 and sprayed onto a carbon surfaceJ the arrows indicate fibrinogen molecules. Scale bars represent 500 nm.

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