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Fert-Butoxycarbonyl, protecting group

Hydrogen bromide may be used to remove either the benzyloxycarbonyl or fert-butoxycarbonyl protecting group. The benzyloxycarbonyl protecting group may also be removed by catalytic hydrogenolysis. Fmoc is removed in base. [Pg.1077]

Amino groups are often protected as their fert-butoxycarbonyl amide (BOC) derivatives. The BOC protecting group is introduced by reaction of the amino acid with di-tcrt-butyl dicarbonate in a nucleophilic acyl substitution reaction (Section 21.5) and is removed by brief treatment with a strong organic acid such as trifluoroacetic acid, CFgCOOH. [Pg.1094]

A related N-terminal-protecting group is fert-butoxycarbonyl, abbreviated Boc ... [Pg.1078]

See other pages where Fert-Butoxycarbonyl, protecting group is mentioned: [Pg.453]    [Pg.95]    [Pg.186]    [Pg.302]    [Pg.199]    [Pg.1171]    [Pg.187]    [Pg.78]    [Pg.203]    [Pg.1168]   


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Butoxycarbonylation

Fert-Butoxycarbonyl group

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