Fert-Amyl alcohol

Tertiary alcohols are more readily dehydrated than seccmdary alcohols, whilst primary alcohols are dehydrated with comparative difficulty. Thus the reaction proceeds easily with 33 per cent, sulphuric acid (1 acid 2 water, by vdume) for fert.-amyl alcohol, bat 60 per cent, (by volume) is required for aec.-amyl alcohol. Higher concentrations of acid tend to lead to increasing pdymerisation of the olefine and are therefore usually avoided. 

Solubility soluble in common solvents, including CHCI3, CH2CI2, Et20, THE, MeCN, PhMe, DMF, fert-amyl alcohol, and MeOH. Slightly soluble in hexanes. Insoluble in H2O. 

FIG. 11 Adsorption isotherms of water for thennolysin immobilized onto Amberlite XAD-7 in ethyl acetate (open circles) and in fert-amyl alcohol (closed circles) at 70°C. (From Ref 59.)... 

More recently, Beller and coworkers have shown that the ruthenium complex 6 (Fig. 7.9) is an effective epoxidation catalyst, for a variety of olefins, with 3 equiv. of 30% H2O2 at very low catalyst loadings (0.005 mol%). A tertiary alcohol such as fert-amyl alcohol was used as a cosolvent. Based on its high activity and broad scope this system appears to have considerable synthetic potential, which may be adapted to afford effective asymmetric variants in the future. Indeed, a truly effective catalyst, with broad scope, for asymmetric epoxidation with aqueous hydrogen peroxide, preferably in the absence of organic solvents, is still an important and elusive goal in oxidation chemistry. 

TAME, DIPE, fert-Amyl Alcohol and Cl to C4 Alcohols in Gasoline by GC... 

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