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MAOIs Fenfluramine

The concurrent use of non-selective MAOIs and amfetamines and related drugs can result in a potentially fatal hypertensive crisis and/or serotonin syndrome. Interactions have been reported for amfetamine, dexamfetamine, metamfetamine, and methylpheni-date. Interactions have also been reported with the illicit drug ecstasy (MDMA, methylenedioxymethamfetamine) when taken with phenelzine or moclobemide. The manufacturers of fenfluramine and dexfenfluramine contraindicated their use with MAOIs. [Pg.1144]

The manufacturer recommended that fenfluramine should not be used in patients with a history of depression, or during treatment with antidepressants (especially the MAOIs), and there should be an interval of 3 weeks between stopping the MAOIs and starting fenfluramine. A woman taking phenelzine developed severe headache, neck stiffness and nausea within an hour of taking fenfluramine 20 mg, and then collapsed and re-... [Pg.1144]

See other pages where MAOIs Fenfluramine is mentioned: [Pg.20]    [Pg.172]    [Pg.194]    [Pg.249]    [Pg.281]    [Pg.281]    [Pg.29]    [Pg.18]    [Pg.172]    [Pg.194]    [Pg.249]    [Pg.281]    [Pg.281]    [Pg.167]    [Pg.18]    [Pg.172]    [Pg.281]    [Pg.281]    [Pg.244]    [Pg.1145]   
See also in sourсe #XX -- [ Pg.1144 ]



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Fenfluramine

MAOI

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