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Genetic engineering fatty acid biosynthesis

Fatty acid synthase. Fatty acid biosynthesis in plants occurs primarily in the plastids and is dependent upon the existence of the fatty acid synthase (or synthetase) II complex (FAS) (Harwood, 1988 Stumpf, 1989). This complex, unlike the system present in animals, is discontinuous (Shimakata and Stumpf, 1982a). Thus it has been possible to isolate and study the associated enzyme activities independently. Purification of each activity to homogeneity can then allow amino acid sequence analysis, cloning and elucidation of the gene, and subsequent application in the genetic engineering of plants. [Pg.62]

Hopwood DA, Sherman DH (1990) Molecular genetics of polyketides and comparison with fatty acid biosynthesis. Annu Rev Genet 24 37-66 Hopwood DA, Malpartida F, Kieser HM, Ikeda H, Duncan J, Fujui I, Rudd BAM, Floss HG, Omura S (1985) Production of hybrid antibiotics by genetic engineering. Nature 314 642-644... [Pg.278]

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