Eye tumor

Eye tumor 141 bp deletion Exons 22-23 (codons Partial loss of binding... 

Studies of the eye tumor retinoblastoma have revealed an Rb locus on the long arm of chromosome 13 that influences retinoblastoma occurrence. Patients with 13q— deletions often develop bilateral tumors (both sides), in contrast to more common forms of retinoblastoma that occur at one site. Which of the following phrases best explains this phenomenon ... 

The radioactive nuclide with the symbol is used to detect eye tumors. What is its atomic number and mass number How many protons and how many neutrons are in the nucleus of each atom Write two other ways to represent this nuclide. 

The first tumor-suppressor gene to be cloned was the retinoblastoma (Rb) gene. Alfred Knudson had been studying the predisposition of children from certain families to have a high rate of retinoblastoma eye tumors. He noticed that the rate of hereditary retinoblastoma in these children was as much as 1000 times higher than expected, compared to the normal population. In addition, hereditary retinoblastoma results in multiple independent tumors in both eyes of the patient, whereas the nonhereditary form is almost always only a single tumor in just one eye. 

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