Experimentation with Dinitrochlorobenzene DNCB

Biopsies are usually done approximately 14 hours after the application of the substance, for at this moment the macroscopic reaction is often optimal. As we have already stated, this permits us to compare the histological reactions obtained by various allergens. 

In certain cases, however, the biopsies have been successively done between the 2nd and 24th hours and even later after the application of the ec2 ema producing substance, in order to follow the evolution of the primary toxic and that of the eczematous reaction. 

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