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Examples of Drugs Derived from Screening Leads

Anhydride, acyi haiide. Epoxide, aziridine orthiirane [Pg.147]

Activated ester or thioester More than one nitro group [Pg.147]

Alkyl chloride, bromide. Any ring larger than [Pg.147]

EXAMPLES OF DRUGS DERIVED FROM SCREENING LEADS [Pg.147]

By its nature, a screening approach to lead identiflcation has the potential to identify not only structurally novel lead compounds, bnt also nnexpected modes of action or allosteric inhibition. In cases for which there is no prior experience with drugging a particular biological target or where the natural ligand is not amenable to rational medicinal chemistry processes, screening may provide the most effective method for lead identification. However, because of the [Pg.147]

IV. Examples of Drugs Derived from Screening Leads... [Pg.147]

IV. EXAMPLES OF DRUGS DERIVED FROM SCREENING LEADS... [Pg.147]

See other pages where Examples of Drugs Derived from Screening Leads is mentioned: [Pg.25]    [Pg.25]    [Pg.200]    [Pg.412]    [Pg.62]    [Pg.208]    [Pg.46]    [Pg.254]    [Pg.2]    [Pg.101]    [Pg.155]    [Pg.16]    [Pg.91]    [Pg.85]    [Pg.10]    [Pg.44]    [Pg.51]    [Pg.189]    [Pg.29]    [Pg.12]    [Pg.138]    [Pg.189]    [Pg.155]    [Pg.2959]    [Pg.14]    [Pg.684]    [Pg.217]    [Pg.242]    [Pg.415]    [Pg.37]    [Pg.122]   


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Drug Screens

Drugs screening

Screening drugs derived from

Screening of leads

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