Exaggerated placental site

This lesion, actually an exuberant, non-neoplastic physiologic hnding that frequently accompanies molar pregnancies, is composed mostly of implantation site intermediate trophoblasts. The constituent cells express human placental lactogen (hPL) and HLA-G. The Ki-67 index in an exaggerated placental site reaction is less than 10% to 15%.2 ... 

Shih IM, Kurman RJ. Ki-67 labeling index in the diffetential diagnosis of exaggerated placental site, placental site trophoblastic tumor, and choriocarcinoma A double immunohistochemi-cal staining technique using Ki-67 and Mel-CAM antibodies. Hum Pathol. 1998 29 27-33. 

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