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Ethynyl-2-methylpyridine

The C NMR spectrum illustrates the connection between earbon hybridisation and C shift on the one hand and Jqh coupling eonstants on the other. [Pg.191]

13Q chemical shifts 8C--------------------------------CH multiplicities. CH coupling constanls (Hz), coupling protons [Pg.191]

Ethynyl-2-methylpyridine heated with piperidine gives a 70% yield of 2-methyl-5-(2-piperidinoethenyl)pyridine (IX-2S3). Similarly, 2-methyl-S-(2-morpholinoethenyl)pyridine is obtained with morpholine. ... [Pg.111]

In the laboratory, selenium dioxide in organic solvents is a good reagent for the oxidation of alkylpyridines to carboxylic acids. " The intermediate aldehydes can be obtained depending on the position of the alkyl side-chain and the substrate/Se02 ratio. The reaction is selective in the case of 5-ethynyl-2-methylpyridine (X-S9) yielding 5-ethynyl-2-picolinic acid in 40% yield. ... [Pg.269]

Miscellaneous Metal-mediated Reactions. The gallium-catalyzed ortAo-ethynylation of phenols has been achieved with chloro- or (iodoethynyl)trimethylsilane and a variety of phenols. GaUium(ni) chloride (0.10 equiv), n-BuLi (0.30 equiv), and 2,6-di-r-butyl-4-methylpyridine (0.10 equiv) in the presence of haloalkyne and phenol in chlorobenzene at 120°C gave 81-90% yield of a variety of D-(trimethylsilylethynyl)phenols (eq 10). ... [Pg.322]

See other pages where Ethynyl-2-methylpyridine is mentioned: [Pg.191]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.167]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.734]    [Pg.95]    [Pg.39]    [Pg.494]    [Pg.615]    [Pg.191]    [Pg.494]    [Pg.682]    [Pg.167]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.191]    [Pg.72]    [Pg.362]   


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Ethynylation

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