Ethyl «-octylphosphonofluoridate

Wu, S.Y., Casida, J.E. (1995). Ethyl octylphosphonofluoridate and analogs optimized inhibitors of neuropathy target esterase. Chem. Res. Toxicol. 8 1070-5. 

FIGURE 57.8. Spectrum of log values of relative inhibitory potency (RIP) = 7i(AChE)/ i(NTE), where = himolecular rate constant of inhibition. As log(RIP) becomes more positive, cholinergic potential increases as log(RIP) becomes more negative, delayed neuropathic potential increases. CPMO-chlorpyrifos methyl oxon. DCV derivatives refer to symmetrical dialkyl-2,2-dichlorovinyl phosphate (dichlorvos) compounds. EOPF - ethyl n-octylphosphonofluoridate. Data from Kropp and Richardson (2003) Richardson (1992) and Wu and Casida (1996). 

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