Ethyl, amine magnesium iodide

The only synthesis of 1-dialkylaminoindazoles is based on a recyclization reaction (83CC1344). Under the action of ethylmagnesium iodide on 4-phenylbenzo-l,2,3-triazine followed by treatment with methyl iodide, the formation of 1-aminoindazole 26a in 44% yield was observed. The same compound (23% yield) with a small amount of amine 26b is formed when methylmagnesium iodide and ethyl iodide are taken instead of ethyl-magnesium iodide and methyl iodide. Supposedly, the reaction occurs as shown in Eq. (7). 

New syntheses of enamino-ketones by the ring-opening of isoxazoles with samarium di-iodide and with pentacarbonyliron, by the reaction of 2-alkyl-thiomethyl-3-alkylthioacrylophenones with amines, and by the intramolecular photoarylation of A -[2-(haloaryl)ethyl]-(3-enaminones, of enamino-diketones by the reaction of (3-chlorosulphonic acid chlorides with amines and by amino-methylenation of cyclic (3-dicarbonyl compounds, and of enamino-esters by aminomethylenation of esters and lactones and by the reaction of nitriles with magnesium enolates have been reported. 

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