4-Ethoxy-2-phenylpyrimidine

The 2-phenyl derivative of 4-ethoxy-l-ethylpyrimidinium tetrafluoro-borate undergoes with liquid ammonia deethylation at N-1 as well as deethoxylation at C-4, a mixture of 4-ethoxy-2-phenylpyrimidine (18) and l-ethyl-4-imino-2-phenylpyrimidine (19), respectively, being obtained (Scheme IIL12) (77RTC183). 

Ethoxy-6-methylpyrimidine 1-oxide (499) reacts with phenyl isocyanate to eliminate carbon dioxide and give a mixture of 4-ethoxy-6-methyl-N-phenylpyrimidin-2-amine (SOO) and (the derived) 7V-(4-ethoxy-6-methylpyrimidin-2-yl)-7V,7V -diphenylurea (SOI) phenyl isothiocyanate reacts quite differently (79CPB2642). 

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