Ethanol, fermentation Pichia stipitis

Jeffries, T. W., Dahn, K., Kenealy, W. R., Pittman, P., Sreenath, H. K., and Davis, B. P., Genetic-engineering of the xylose-fermenting yeast Pichia-Stipitis for improved ethanol-production. Abstracts of Papers of the American Chemical Society 1994, 207, 167-BTEC. 

Although many facultatively fermentative yeasts utilize xylose as the carbon source for growth, the ability of these yeasts to produce ethanol from xylose is limited. Yeast strains that utilize xylose often produce xylitol from xylose extra-cellularly as a normal metabolic activity. However, only a few can produce significant quantities of ethanol. The prominent strains that produce ethanol from xylose include Pachysolen tannophilus, Candida shihatae and Pichia stipitis. However, the efficient production of ethanol from xylose is limited by the regulation of dissolved oxygen as well as by the imbalance of cofactors in the metabolic pathway during xylose utilization. In recent years, much effort has been put into improving yeast strains in order to produce ethanol from xylose more efficiently. 

Fermentation of Acid-pretreated Corn Stover to Ethanol Without Detoxification Using Pichia stipitis... 

Huang, C. F., Lin, T. H., Guo, G. L., Hwang, W. S. (2009). Enhanced ethanol production by fermentation of rice straw hydrolysate without detoxification using a newly adapted strain of Pichia stipitis. Bioresource Technology, 100, 3914—3920. 

Jeong, S.M., Kim, Y.J., Lee, D.H., 2012. Ethanol production by co-fermentation of hexose and pentose from food wastes using Saccharomyces coreanus and Pichia stipitis. Korean Journal of Chemical Engineering 29 (8), 1038—1043. 

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