Esterification phenacyl esters

Carboxylic acids are protected as their esters such as methyl esters, tert-hutyl esters, allyl esters, benzyl esters, phenacyl esters and alkoxyalkyl esters. The esters are formed by the reaction of carboxylic acid with alcohol, and the reaction is known as esterification. [Pg.45]

Esterifications involving other acid 2.4.6 Phenacyl esters phenacyl bromide ... [Pg.11]

The haloacetophenone type of polymer reacted with N-protected amino acids and peptides — as already known from esterifications with the monomer reagent in conventional syntheses [74] — under milder conditions but in better loading yield compared to chloromethylated polystyrene, resulting in enhanced reactivity of the peptide phenacyl ester bond on polymer towards nucleophilic cleavage reagents [74—76]. (For further details on peptide cleavage, see Sect. 3.5.)... [Pg.25]

Polymer-supported podands appear to be more commonly used in solid-liquid systems. A variety of chemical transformations including nucleophilic substitutions at saturated carbon atoms [214,215], esterifications [214], sodium bo-rohydride reduction [214], fluoride-catalyzed Michael addition [214], phenacyl ester synthesis, Darzen s reaction, Wittig alkenylation, and dichlorocarbene reactions can be carried out under these conditions [214],... [Pg.309]