Esterification, of monosaccharides

Synthesis. - In a theoretical study on die aBi dation and esterification of monosaccharides, the reactions of 1,6-anhydrO P-D-galactopyranose under diase transfer conditions have been conadered. A MNDO-PM3 study on the sdective activation of 1-0-methoxyacetyl sugars by Zn(II) or Y(in) ions endeavours to explain why 1-0-methoxyacetates are the best donOTs among glycosyl-esters in Lewis add-promoted glycoqiations. ... 

Esterification of monosaccharides is achieved by reaction of the sugar with an acyl halide or an acid anhydride. Acetylation, for instance with acetic anhydride, is carried out in pyridine solution ... 

Most studies of enzymatic sugar ester synthesis have focused on the esterification of monosaccharides, since the problems with poor substrate miscibility increase significantly with increasing size of the carbohydrate. However, by careful choice of reaction conditions it has been shown possible to acylate several di- and trisaccharides efficiently. Solvent mixtures of 2-methyl-2-butanol and dimethylsulfoxide have thus been used in... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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