Establishment of 1,1-Thio Linkages

1-Thiosucrose, the true analog of sucrose, was first obtained in 1984 [23] by Lewis acid catalysed glycosylation using tetra-0-acetyl-1-thio-a-D-glucose (162) (not 

Most 1,2-thio linkages have been established via Sn2 displacement of a triflate of either glucosyl or mannosyl acceptor molecules with 1-thiolates. 

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