ESI-MS Studies in Stille Cross-Coupling Reactions

The Stille reaction is the palladium-catalyzed coupling of unsaturated halides or triflates with organostaimanes [34]. The accepted mechanism for this reaction is based on the three steps which typically work for this type of cross oupling  

Several new species involved in the transmetalation step were now detected the radical cation 159 derived from a neutral species and the cationic homolog 160. Tin-containing species 161 was also observed and assigned as another transmetalation product. At m/z = 657, species 162 might proceed from neutral species [ArPd 

ESI-MS Studies in Palladium-Catalyzed Reactions Involving Allenes 

At the beginning of the reaction, the first species observed was intermediate 163, which may proceed from the intermediate 164. It was suggested that 164 was the result of an oxidative addition of acetic acid to a Pd(0) complex In a later injection. 

6 ESI-MS Studies in Paiiadium-Catat fzed Reactions Involving Allenes 255 

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