Erythromycin physicochemical properties

Specialized antibiotic formulations have been developed for DCT, with physicochemical properties chosen to confer prolonged retention in the mammary secretions (21,, ). Ziv ( ) has summarized the desirable kinetic and other properties of such a product. The following antibiotic formulations are presently approved by the U.S. Center for Veterinary Medicine, FDA for infusion into the dry mammary gland erythromycin (300 mg), oxytetracycline-HCl (426 mg), benzathine cloxacillin (500 mg), cephapirin benzathine (300 mg), novobiocin (400 penicillin (200,000 lU) novobiocin (400 mg), penicil-... 

Nakagawa, Y., Itai, S., Yoshida, T., and Nagai,T. (1992), Physicochemical properties and stability in the acidic solution of a new macrolide antibiotic, clarithromycin, In comparison with erythromycin, Chem. Pharm. Bull., 40,725-728. 

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