Ervatamia coronaria alkaloids

The related alkaloids ervaticine (15) and apparicine (16a) have been isolated from the leaves of Ervatamia coronaria (85H(23)2975) and from the wood of Vallesia antillana (77MI249), respectively. The latter exhibits high antibacterial activity. Subsequently, 16(S)-hydroxy-16,22-dihydroapparicine (16b) was isolated from the leaves of T. dichotoma (84JNP835). 

Catharanthine-Ibogamine-Cleavamine Group. The chemistry and pharmacology of alkaloids of Tabernanthe iboga have been reviewed." New extractions have resulted in the isolation of coronaridine (previously observed), voacangine, isovoacangine, and ibogamine from the bark of Ervatamia coronaria, coronaridine and 19-oxocoronaridine from the roots of Tabernaemontana... 

Joshi, A. B. Satyanarayana, D. Chandrashekar, K. S. Subrahmanyam, E. V. S. Isolation and characterization of indole alkaloids from the flowers of Ervatamia coronaria (Syn Taberaemontana divari-cata). Nat. Prod. Sci. 2004,10, 96-98. 

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