Epimers Epinephrine

Epimerization of sugar, mechanisms 778 Epimers, definition of 163 Epinephrine (adrenaline) 542,553, 553s Episomes. See plasmid Epithelial cells 29 Epitheliocytes 25 Epoxides, alkyation by 254 Epoxide hydrolases 591 EPR (electron paramagnetic resonance) spectroscopy 398, 399 of glutamate mutase 873 in study of phosphotransferases 639 EPSP (enolpyruvoylshikimate-3-phosphate) 687s... 

Epinephrine (adrenaline) was one of the first hormones for which differential effects on blood pressure were reported for the two epimers in the early 20th century [58]. A reassessment of epinephrine activity was made by analyzing the effects of optical isomers of ephedrine and methylephedrine on the spontaneous beating rate of the isolated right atrium of normal and reserpinized rats by investigating direct and indirect actions on al-adrenoceptors. L-ephedrine, and to a lesser extent D-ephedrine, markedly increased the beating rate of rat right atrium [59]. 

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